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KMID : 0191120000150010099
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Journal of Korean Medical Science
2000 Volume.15 No. 1 p.99 ~ p.102
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A case of Goodpasture´s syndrome with massive pulmonary hemorrhage
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Kim YO
Choi JY/Park JI/Yoon SA/Yang CW/Hyoung K/Bang BK
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Abstract
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We present a typical case of Goodpasture´s syndrome with massive pulmonary hemorrhage and acute
deterioration of renal function. A 20-year-old male was admitted due to severe azotemia (blood
urea nitrogen 214.7 mg/dL, serum creatinine 30.2 mg/dL) and was treated with emergency hemodialysis.
On the 4th hospital day, a sudden onset of pulmonary hemorrhage developed. The circulating level of
anti-glomerular basement membrane antibody was then elevated highly, and the kidney biopsy showed
crescentic glomerulonephritis and linear deposition of IgG along the glomerular capillary. The patient
was treated with intravenous high dose-steroid, oral cyclophosphamide and plasma exchanges. The
pulmonary hemorrhage improved with the therapy, however, his renal function did not improve. He is
currently on a regular schedule of hemodialysis.
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KEYWORD
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